Filed pursuant to Rule 424(b)(3)

Registration Number 333-198502

Prospectus Supplement No. 4 (To prospectus dated September 11, 2014)

5,768,470 Shares of Common Stock

Sysorex Global Holdings Corp.

This Prospectus Supplement No. 4 (the “Prospectus Supplement”) supplements our Prospectus dated September 11, 2014, as supplemented by Prospectus Supplement Nos. 1, 2, and 3 dated October 9, 2014, November 3, 2014, and November 18, 2014, respectively (collectively, the “Prospectus”), relating to the offer and sale of up to 5,768,470 shares of common stock, par value $0.001, of Sysorex Global Holdings Corp., a Nevada corporation (the “Company,” “Sysorex,” “us,” “our,” or “we”) by the selling stockholders identified on page 40 of the Prospectus. We are not selling any securities under this Prospectus Supplement and the Prospectus and will not receive any of the proceeds from the sale of shares by the selling stockholders.

The selling stockholders may sell the shares of common stock described in the Prospectus in a number of different ways and at varying prices.  See “Plan of Distribution” in the Prospectus for more information about how the selling stockholders may sell the shares of common stock being registered pursuant to this Prospectus Supplement and Prospectus.

We will pay the expenses incurred in registering the shares, including legal and accounting fees. See “Plan of Distribution” in the Prospectus.

We are an “emerging growth company” under the Federal Securities laws and are subject to reduced public company reporting requirements as set forth on page 5 of Prospectus.  Our common stock is currently quoted on the Nasdaq Capital Market under the symbol “SYRX”.  On February 2, 2015, the last reported sale price of our common stock on the Nasdaq Capital Market was $1.49. 

Recent Developments

This Prospectus Supplement is being filed to update and supplement the information in the Prospectus with the information contained in our Current Reports on Form 8-K filed with the Securities and Exchange Commission on January 30, 2015 and February 5, 2015 (the “Current Reports”). Accordingly, we have attached the Current Reports to this Prospectus Supplement. Any statement contained in the Prospectus shall be deemed to be modified or superseded to the extent that information in this Prospectus Supplement modifies or supersedes such statement. Any statement that is modified or superseded shall not be deemed to constitute a part of the Prospectus except as modified or superseded by this Prospectus Supplement.

This Prospectus Supplement should be read in conjunction with, and may not be delivered or utilized without, the Prospectus.

In reviewing this Prospectus Supplement, you should carefully consider the matters described under the caption “Risk Factors” beginning on page 9 of the Prospectus.

Neither the U.S. Securities and Exchange Commission nor any state securities commission has approved or disapproved these securities or determined if this Prospectus Supplement is truthful or complete. Any representation to the contrary is a criminal offense.

This Prospectus Supplement does not constitute an offer to sell or the solicitation of an offer to buy any securities.

The date of this Prospectus Supplement is February 5, 2015

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 OR 15(d) of The

Securities Exchange Act of 1934

Date of report (Date of earliest event reported):  January 30, 2015 (January 26, 2015)

SYSOREX GLOBAL HOLDINGS CORP.

 (Exact name of registrant as specified in charter)

Registrant’s telephone number, including area code: (408) 702-2167

No change

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K is intended to simultaneously satisfy the filing obligation of the Registrant under any of the following provisions:

Effective January 26, 2015, the board of directors of Sysorex Global Holdings Corp. (the “Company”) appointed Wendy Loundermon as the Company’s interim Chief Financial Officer, replacing William Frederick who resigned as the Company’s Chief Financial Officer on that date.

Ms. Loundermon, age 44, has been with the Company since 2002, previously serving as Chief Financial Officer and, prior to her re-appointment as Chief Financial Officer, serving as the Company’s Vice President of Finance and Secretary. In addition, Ms. Loundermon serves as President, Chief Financial Officer and Secretary of Sysorex Government Services, Inc., a wholly-owned subsidiary of the Company, Secretary and Vice President of Sysorex Federal, Inc., a wholly-owned subsidiary of the Company, and Secretary of AirPatrol Corporation, Lilien Systems and Shoom, Inc., each a wholly-owned subsidiary of the Company.

The Employment Agreement, effective as of October 1, 2014, between Ms. Loundermon and the Company (the “Loundermon Employment Agreement”), the material terms of which are summarized on page 3 of the Company’s Current Report on Form 8-K under Item 5.02 filed on October 27, 2014, to which the Loundermon Employment Agreement is attached as an exhibit, remains in effect without modification.

Ms. Loundermon does not have any family relationships with any of the officers or directors of the Company. 

Ms. Loundermon does not have an interest in any transaction required to be reported pursuant to Item 404(a) of Regulation S-K under Securities Act of 1933, as amended.

On January 30, 2015, the Company issued a press release announcing Ms. Loundermon’s re-appointment as the Company’s interim Chief Financial Officer. A copy of the press release is attached herewith as Exhibit 99.1. 

The foregoing information (including the exhibit hereto) is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, except as expressly set forth by specific reference in such filing.

(1) Incorporated by reference to the Company’s Current Report on Form 8-K filed on October 27, 2014.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Exhibit 99.1

Sysorex Announces Management Change

Palo Alto, CA -- Sysorex (NASDAQ: SYRX) (the “Company”), a global technology leader specializing in big data analytics and location-based mobile solutions for the private and public sectors announced a management change.

The Company has appointed Wendy Loundermon as its interim Chief Financial Officer. Ms. Loundermon replaces Will Frederick, who has resigned to pursue other interests, and management has begun the search for a permanent successor.

“We thank Will for his contributions during his time with the Company and wish him well,” said Mr. Ali.

Ms. Loundermon, age 44, comes to the position with over 20 years of financial experience. Ms. Loundermon joined the Company in 2002 and had been the CFO until October 2014. Prior to her re-appointment as Chief Financial Officer, Ms. Loundermon was serving as the Company’s Vice President of Finance and Secretary and continues to serve as President, Chief Financial Officer and Secretary of its Sysorex Government Services subsidiary. Ms. Loundermon is a CPA, and holds a Masters in Taxation and a B.S. in Accounting from George Mason University.

“Wendy is a veteran on our team since joining the Company in 2002 and was instrumental in our 2014 IPO on NASDAQ. Her previous Sysorex experience also includes our rapid expansion during 2011 through 2014, and I am confident that she will help us move through the next phase in our business," continued Mr. Ali.

About Sysorex Global Holdings Corp.

Through focused, custom technology solutions, Sysorex (NASDAQ:SYRX) provides cyber security, data analytics, custom application development, cloud solutions, Mobile/BYOD solutions and strategic outsourcing to government and commercial clients in major industries around the world. From identifying security risks to helping clients realize value from their big data strategies, Sysorex has the experience, technology, partners, and agility to be your trusted IT partner. Visit www.sysorex.com, follow @Sysorex and Like us on Facebook.

Sysorex Investor Relations Contact:

Scott Arnold

Managing Director

CorProminence LLC

377 Oak Street

Concourse 2

Garden City, NY 11530

+1-516-222-2560

www.corprominence.com

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 OR 15(d) of The

Securities Exchange Act of 1934

Date of report (Date of earliest event reported):  February 5, 2015 (January 30, 2015)

SYSOREX GLOBAL HOLDINGS CORP.

 (Exact name of registrant as specified in charter)

Registrant’s telephone number, including area code: (408) 702-2167

No change

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K is intended to simultaneously satisfy the filing obligation of the Registrant under any of the following provisions:

On January 30, 2015 (the “Execution Date”), Sysorex Global Holdings Corp. (the “Company”) and Mr. William Frederick entered into a release agreement (the “Release Agreement”) in connection with Mr. Frederick’s resignation as the Company’s Chief Financial Officer, effective as of January 26, 2015.

In accordance with the Release Agreement, subject to the terms and conditions therein, Mr. Frederick agreed to release any and all claims he may have against the Company and all of its past and present employees, officers, directors, stockholders, owners, representatives, assigns, attorneys, agents, insurers, employee benefit programs (and the trustees, administrators, fiduciaries and insurers of such programs) (the “Releasees”) and any other persons acting by, through, under or in concert with any of such Releasees in connection with Mr. Frederick’s employment with the Company, or the termination of that employment, and in consideration for the release the Company agreed to pay severance to Mr. Frederick in the amount of approximately $62,500 to be paid in three equal monthly installments beginning on the eighth day following the Execution Date. In addition, except as specifically set forth in the Release Agreement, on the eighth day following the Execution Date, that certain Employment Agreement, by and between the Company and Mr. Frederick, effective as of October 1,2014, shall be deemed terminated and of no further force and effect.

Mr. Frederick will have seven days following the Execution Date to revoke the Release Agreement.

The foregoing description of the terms and conditions of the Release Agreement does not purport to be complete and is qualified in its entirety by reference to the full text of the Release Agreement, a copy of which is filed as Exhibit 10.1 hereto and incorporated herein by reference.

(d) Exhibits.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Exhibit 10.1

RELEASE AGREEMENT

This Release Agreement (“Agreement”) is entered into by and between Sysorex Global Holdings Corp. ("Sysorex") and William Frederick, an individual (“Employee”), as of January 26, 2015, based upon the following:

RECITALS

Whereas, Sysorex and Employee wish to memorialize their agreement regarding the termination of Employee’s employment with Sysorex and the consideration that is to be transferred or paid to Employee in exchange for this Agreement; and

Whereas, Sysorex and Employee wish to memorialize their agreement regarding Employee’s waiver and release of all rights and claims that he may have against Sysorex, if any.

Now, therefore, in consideration of the mutual covenants and promises contained herein and for other valuable consideration, the receipt and sufficiency of which is hereby acknowledged, Sysorex and Employee agree as follows:

AGREEMENT

1.         Incorporation of Recitals. The recitals to this Agreement are an integral part of this Agreement and are hereby incorporated as a part of this Agreement as if set forth in it.

2.         Payments to Employee. In exchange for Employee’s release of Sysorex from any past, present and future obligations (if any), whether monetary or otherwise, allegedly owed by Sysorex to Employee based upon Employee’s employment and the termination thereof, Sysorex shall make the following payments (less standard employee withholdings) to Employee, in addition to the amount referenced in Section 3 hereof and wages earned up to and including January 26, 2015: (a) $20,833.33 on the eighth (8^th) day after the execution of this Agreement; (b) $20,833.33 on the thirty-eighth (38th) day after the execution of this Agreement; and (c) $20,833,333.33 on the sixty-eighth (68th) day after the execution of this Agreement. If any of the foregoing payments come due on a weekend day or a company holiday, the payment will be made the following business day.

3.         Accrued Vacation. Sysorex shall pay to Employee $4,687.50, which represents the amount owed to Employee for his unused, accrued vacation time (less standard employee withholdings).

4.         Waiver of All Claims. Employee agrees that he is not entitled to receive, will not claim and expressly waives any entitlement to rights, benefits or compensation from Sysorex other than as expressly set forth in this Agreement.

5.         Complete Release by Employee.

(a)         Release. Employee irrevocably and unconditionally releases all of the claims described in subsection (b) of this Section 5 that he may now have against the following persons or entities (the “Releasees”): Sysorex, all of its past and present employees, officers, directors, stockholders, owners, representatives, assigns, attorneys, agents, insurers, employee benefit programs (and the trustees, administrators, fiduciaries and insurers of such programs) and any other persons acting by, through, under or in concert with any of the persons or entities listed in this subsection.

(b)         Claims Released. The claims released include all claims, promises, debts, causes of action or similar rights of any type or nature Employee has or had which in any way relate to (i) Employee’s employment with Sysorex, or the termination of that employment, such as claims for compensation, bonuses, commissions, lost wages or unused accrued vacation or sick pay, (ii) the design or administration of any employee benefit program or Employee’s entitlement to benefits under any such program, (iii) any claims to attorneys’ fees and/or other legal costs and (iv) any other claims or demands Employee may, on any basis, have. The claims released include, but are not limited to, claims arising under any of the following statutes or common law doctrines:

(i)         Anti-Discrimination Statutes, such as the Age Discrimination in Employment Act, which prohibits age discrimination in employment; the Civil Rights Act of 1991, Title VII of the Civil Rights Act of 1964, and §1981 of the Civil Rights Act of 1866, which prohibit discrimination based on race, color, national origin, religion or sex; the Equal Pay Act, which prohibits paying men and women unequal pay for equal work; the Americans With Disabilities Act, which prohibits discrimination against the disabled; the California Fair Employment and Housing Act, which prohibits discrimination in employment based upon race, color, national origin, ancestry, physical or mental disability, medical condition, marital status, sex, or age; and any other federal, state or local laws or regulations prohibiting employment discrimination.

(ii)        Federal Employment Statutes, such as the Employee Retirement Income Security Act of 1974, which, among other things, protects pension or health plan benefits; and the Fair Labor Standards Act of 1938, which regulates wage and hour matters.

(iii)       Other Laws, such as any federal, state or local laws restricting an employer’s right to terminate employees or otherwise regulating employment; any federal, state or local law enforcing express or implied employment contracts or requiring an employer to deal with employees fairly or in good faith; and any other federal, state or local laws providing recourse for alleged wrongful discharge, physical or personal injury, emotional distress, fraud, negligent misrepresentation, libel, slander, defamation and similar or related claims. The laws referred to in this paragraph include statutes, regulations, other administrative guidance and common law doctrines.

(c)         Release Extends to Both Known and Unknown Claims. This release covers both claims that Employee knows about and those Employee does not know about. Employee understands the significance of this release of unknown claims and his waiver of any statutory protection against a release of unknown claims. Employee expressly waives the protection of any such governmental statutes or regulations.

More particularly, and without limitation, Employee acknowledges that Employee has read and is familiar with and understands the provisions of Section 1542 of the California Civil Code, which provides: “A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS FAVOR AT THE TIME OF EXECUTING THE RELEASE, WHICH, IF KNOWN TO HIM MUST HAVE MATERIALLY AFFECTED HIS SETTLEMENT WITH THE DEBTOR.”

EMPLOYEE EXPRESSLY WAIVES ANY RIGHT OR CLAIM OF RIGHT EMPLOYEE MAY HAVE UNDER SECTION 1542 OF THE CALIFORNIA CIVIL CODE.

(d)         Ownership of Claims. Employee represents that he has not assigned or transferred, or purported to assign or transfer, all or any part of any claim released by this Agreement.

6.         Employee’s Promises. In addition to the release of claims provided for in section 5, Employee promises never to file or prosecute a lawsuit, arbitration, administrative complaint or charge, or other complaint or charge asserting any claims that are released by this Agreement. Employee represents that he has not filed or caused to be filed any lawsuit, arbitration, complaint or charge with respect to any claim this Agreement releases. Employee further agrees to request any government agency or other body assuming jurisdiction of any complaint or charge relating to a released claim to withdraw from the matter or dismiss the matter with prejudice.

7.         Consequences of Employee’s Violation of Promises. If Employee breaks any of the promises in this Agreement, such as, by way of example and not by way of limitation, by filing or prosecuting a lawsuit, arbitration or charge based on claims that Employee has released, or if any representation made by Employee in this Agreement was false when made, Employee will pay reasonable attorneys’ fees and all other costs incurred as a result of such breach or false representation, such as, by way of example and not by way of limitation, Sysorex's cost of defending any suit brought with respect to a claim released by him.

8.         Consulting with Attorney. Employee acknowledges that Sysorex has advised him to obtain the services of an attorney to review this Agreement and to advise him regarding it. Employee acknowledges he has had ample opportunity to consult with an attorney prior to executing this Agreement.

9.         Period for Consideration of Agreement. Employee acknowledges that Employee was given a period of twenty-one (21) days to review and consider this Agreement before signing it and has a seven (7) day period following its execution to revoke it. Employee further acknowledges that: (1) Employee took advantage of this period to consider this Agreement before signing it; (2) Employee carefully read this Agreement; and (3) Employee fully understands this Agreement and is entering into it voluntarily and without coercion or duress.

10.       Severability. The provisions of this Agreement are severable. If any part of it is found to be unenforceable, all other provisions shall remain fully valid and enforceable.

11.       Choice of Laws. This Agreement shall be governed by the laws of the State of California.

12.       Nature, Effect and Interpretation of this Agreement.

(a)         Entire Agreement. This is the entire Agreement between Employee and Sysorex; it may not be modified or cancelled in any manner except by a writing signed by both Sysorex and Employee. Sysorex has made no promises or representations to Employee other than those in this Agreement and Employee has made no promises or representations to Sysorex other than those in this Agreement. The headings included in this Agreement are for convenience only and do not limit, alter, or affect the matters contained in this Agreement or the paragraphs they encaption.

(b)         Employment Agreement. On the eighth day following the execution of this Agreement, the Employment Agreement between Sysorex and Employee, effective as of October 1, 2014 (the “Employment Agreement”), shall be deemed terminated and be of no further force and effect, except that Sections 8 and 9 and the first two sentences of Section 12 of the Employment Agreement shall survive and continue in effect.

(c)         Successors and Assigns. This Agreement shall bind both Sysorex's and Employee’s heirs, administrators, representatives, executors, successors and assigns, and shall inure to the benefit of all Releasees and their respective heirs, administrators, representatives, executors, successors and assigns.

(d)         Interpretation. This Agreement shall be construed as a whole according to its fair meaning, and not strictly for or against any of the parties. Unless the context indicates otherwise, the term “or” shall be deemed to include the term “and” and the singular or plural number shall be deemed to include the other. Paragraph headings used in this Agreement are intended solely for convenience of reference and shall not be used in the interpretation of any of this Agreement. It is acknowledged that neither party shall be construed to be solely responsible for the drafting hereof, and therefore any ambiguity shall not be construed against either party as the alleged draftsman of this Agreement.

(e)         Counterparts and Emailed Signatures. For the convenience of the parties to this Agreement, this document may be executed by signatures sent via email and in counterparts that shall together constitute the agreement of the parties as one and the same instrument.

(f)         Implementation. Sysorex and Employee both agree that, without the receipt of further consideration, they will sign and deliver any documents and do anything else that is necessary in the future to make the provisions of this Agreement effective.

13.       Notices. Unless otherwise specifically provided in this Agreement, all notices, demands, requests, consents, approvals or other communications (collectively and severally called “Notices”) required or permitted to be given hereunder, or which are given with respect to this Agreement, shall be in writing, and shall be given by: (1) personal delivery (which form of Notice shall be deemed to have been given upon delivery), (2) by telegraph or by private airborne/overnight delivery service (which forms of Notice shall be deemed to have been given upon confirmed delivery by the delivery agency), (3) by electronic or facsimile or telephonic transmission, provided the receiving party has a compatible device or confirms receipt thereof (which forms of Notice shall be deemed delivered upon confirmed transmission or confirmation of receipt), or (4) by mailing in the United States mail by registered or certified mail, return receipt requested, postage prepaid (which forms of Notice shall be deemed to have been given upon the fifth (5th) business day following the date mailed). Notices shall be addressed to the parties as follows:

14.         Arbitration. Any controversies or claims arising out of or relating to this Agreement shall be fully and finally settled by arbitration held in Palo Alto, California in accordance with the National Rules for the Resolution of Employment Disputes of the American Arbitration Association then in effect (the "AAA Rules"), conducted by one arbitrator either mutually agreed upon by Sysorex and Employee or chosen in accordance with the AAA Rules, except that the parties thereto shall have any right to discovery as would be permitted by the California Rules of Civil Procedure for a period of 90 days following the commencement of such arbitration and the arbitrator thereof shall resolve any dispute which arises in connection with such discovery. Notwithstanding anything to the contrary in this Section 14, Sysorex may seek provisional injunctive relief from any court of competent jurisdiction in aid of the arbitration, to prevent any award from being rendered ineffectual, or to enforce its rights under Section 8 and/or 9 of the Employment Agreement. Seeking such relief shall not result in a waiver of any right to compel arbitration.

15.         Representation of Authority. Each party executing this Agreement on behalf of any party expressly represents and warrants that he or she has authority to execute and thereby bind the party on behalf of whom he or she executes this Agreement to the terms of this Agreement and agrees to indemnify and hold harmless each other party from any claim that such authority did not exist.

Executed on January 30, 2015.

6